MSC Ph.D: Experienced Medical pharmaceutical consultant with track record of achievements across Global, Regional and Local pharma business. Experienced in Medical Affairs, Clinical development and Medical Publications across therapeutic areas (Cardiovascular expertise, Vaccines). Team player with strong organizational skills and ability to handle multiple projects simultaneously with a high degree of accuracy.
Certified Pharmacologist
Publications
(1) De Mulder PA, Van Kerckhoven R, Adriaensen HF, Gillebert TC, De Hert SG. Continuous total intravenous anesthesia, using propofol and fentanyl in an open‑thorax rabbit model: evaluation of cardiac contractile function and biochemical assessment. Laboratory Animal Science 1997; 47(4): 367‑75.
(2) De Mulder PA, De Hert SG, Van Kerckhoven R, Adriaensen HF, Gillebert TC. Sodium nitroprusside enhances in vivo left ventricular function in beta‑adrenergically stimulated rabbit hearts. Cardiovascular Research 1998;38(1):133‑9.
(3) Van Kerckhoven R, Kalkman EAJ, Saxena PR, Schoemaker RG. Altered cardiac collagen and Associated changes in diastolic function of infarcted rat hearts. Cardiovascular Research 2000; 46(2):316‑23.
(4) Van Kerckhoven R, van Veen TAB, Boomsma F, Saxena PR, Schoemaker RG. Chronic administration of moxonidine suppresses sympathetic activation in a rat heart failure model. European Journal of Pharmacology 2000;397(1):113‑120.
(5) Van Kerckhoven R, Saxena PR, Schoemaker RG. Restored capillary density in the spared myocardium of infarcted rats improves ischemic tolerance. Journal of Cardiovascular Pharmacology 2002; 40(3): 370‑380.
(6) Van Kerckhoven R, Lankhuizen I, van Veghel R, Saxena PR, Schoemaker RG. Chronic vasopressin V1A‑ but not V2 antagonism prevents heart failure in chronically infarcted rats. Europan Journal of Pharmacology 2002;449(1‑2): 135‑141.
(7) Van Kerckhoven R, van Veghel R, Saxena PR, Schoemaker RG. Lower intrinsic rather than in vivo heart rate contributes to capillary growth in infarcted rat hearts.
(8) Van Kerckhoven R, Saxena PR, Schoemaker RG. Pharmacological therapy can increase capillary density in post‑infarction remodeled rat hearts. Cardiovascular Research 2004; 61 (3): 620‑629.
(9) Lacour C, Roccon A, Galindo G et al. Effects of differential blockade of the renin‑angiotensin system in postinfarcted rats. Fundamental & Clinical Pharmacology 2004; 18: 299‑307.
(10) Guiraudou P, Pucheu SC, Gayraud R, Gautier P et al. Involvement of nitric oxide in amiodarone and dronedarone‑induced coronary vasodilation in guinea pig heart. European Journal of Pharmacology 2004; 496: 119‑127.
(11) Rademakers LM, Van Kerckhoven R, van Deursen CJM , Kevin Vernooy et al. Myocardial infarction does not preclude electrical and hemodynamic benefits of CRT in dyssynchronous canine hearts. Circulation Arrhythm Electrophysiol. 2010;3(4):361‑8.
(12) Fuchs D, de Graaf Y, Van Kerckhoven R and Draijer R. Effect of Tea Theaflavins and Catechins on Microvascular Function. Nutrients 2014; 6 (12): 5772‑5785