Priscilla Van Den Ackerveken
Flémalle
Summary
Passionate R&D scientist with 10+ years of expertise in biomarker discovery, diagnostic innovation, and translational research. I thrive on solving complex scientific challenges through strategic thinking, cross-disciplinary collaboration, and bold innovation. As a leader, I foster high-performing teams, drive ISO-13485-compliant projects, and turn visionary ideas into tangible breakthroughs. Published author (10+ papers) and inventor (4 patents), I am committed to pushing the boundaries of biomedical research to create real-world impact.
Overview
14
14
years of professional experience
Work History
Head of Translational Science Unit
Volition Rx
Isnes
05.2023 - Current
- Oversaw teams of up to nine people, responsible for conducting translational research.
- Collaborated with cross-functional teams and partners (academic institutions, biotech/pharma partners, CROs) to ensure the successful completion of projects
- Leading translational research activities in compliance with ISO 13485.
- Write and review reports and scientific publications: Co-authored 10 or more scientific publications.
- Involved in grant application (Biowin / Walloon region) processes and lead their management.
- Define and manage a budget of up to €300,000 related to the projects/unit.
- Define department objectives, strategy, and KPIs.
- Collaborated closely with the IP team to file patents: filed four patents as an inventor.
- Provided support and guidance to colleagues to maintain a collaborative work environment.
- Utilized advanced technical skills and expertise to troubleshoot complex problems and implement solutions.
- Managed time effectively to ensure tasks were completed on schedule and deadlines were met.
- Presented progress reports on R&D projects to executive management team members
- Collaborated with marketing staff to ensure successful product launches.
- Maintained relationships with external partners involved in research activities.
- Assist in securing grants, funding, and investment.
R&D Project Manager and Team Leader
Volition Rx
Isnes
09.2017 - 05.2023
- Oversaw teams of up to 3 people responsible for conducting translational research and assay development (ELISA).
- Work in an ISO-13485 environment.
- Presented progress reports on R&D projects to executive management team members.
- Manage multiple R&D projects, including Gantt chart and people
- Assessed task completion to meet tight project deadlines.
- Identified potential risks associated with R&D projects and developed strategies to mitigate them.
- Encouraged team collaboration and motivated individual employees through positive reinforcement and technical recognition.
Senior R&D Reserach Scientist (Post-doc)
ULiège
Liège
08.2015 - 07.2017
- Conduct research experiments in the field of neuroscience (GIGA-Neurosciences).
- Lead and support a team of lab technicians, PhD students, and postdocs, offering mentorship, guidance, support, and promoting a collaborative and innovative research environment.
- Interpreted test results and determined need for retesting.
- Presented research findings at national and international conferences.
- Reviewed journal articles for publication in scientific journals.
- Teaching “Digestive System Physiology” (BAC2 in Dietetics) and “Neuroinflammation and Neuroimmunology” (Master2 SBIM)
R&D Scientist ( PhD Student)
ULiège
Liège
10.2010 - 07.2015
- Conduct research experiments in the field of Neuroscience (GIGA-Neurosciences)
- Conducted literature reviews to identify relevant sources of information for research projects.
- Presented results of research projects at conferences, workshops and seminars.
- Provided guidance to junior researchers regarding best practices in conducting investigations.
- Collaborated with other researchers in the field to further develop research objectives.
Education
Bioasafety
UNamur
Namur, Belgium09-2022
Ph.D. - Biomedical And Pharmacentical Sciences
ULiège
Liège, Belgium07-2015
FELASA C
ULiège
Liège, Belgium01-2010
Skills
- Biomarker discovery and validation
- Cross-functional team collaboration
- Supervision and leadership
- Develop and validate new analytical methods to support service activities
- Project management: Develop project plans, timelines, and budgets, ensuring efficient use of resources
- Provide technical and scientific support to internal and external partners
- Assist in securing grants, funding, and investment
- Highly organized, with strong attention to detail
- Goal-oriented and solution-oriented mindset
- Effective multitasker
- Quick learner, highly self-motivated, and adaptable to change
- Innovative problem-solving and brainstorming
Accomplishments
- 2013 - 2010 : FRIA/FNRS
- 2010: Best Master’s Thesis Award (Uliège)
Languages
French
First Language
English
Upper Intermediate (B2)
B2
Others Skills
- Laboratory and Technical skills
- Histology & Imaging: Cryostat sectioning, immunostaining, in situ hybridization, confocal microscopy
- Molecular Biology & Cloning: Vector construction, site-directed mutagenesis, molecular cloning techniques
- PCR & qPCR: Conventional PCR, quantitative PCR (qPCR), RT-qPCR, assay development, primer design
- Immunoassays & Protein Analysis: ELISA, Western blot, immunoprecipitation, assay development and analytical validation
- Nucleic Acid Extraction & Analysis: DNA/RNA extraction, quality assessment, quantification
- In vivo and in vitro models
Websites
Catalog of Patents I hold as an Inventor
- Use of cell free nucleosomes as biomarkers (WO2024/240939)
- Recombinant nucleosome materials (WO2024208912A1)
- Proteinsand methodsfor isolating circulating nucleosomes(WO/2024/153619)
- Method for the detection of blood cancer (WO/2023/105062)
List of Scientific publications
- Two other papers are currently under submission / review in peer-reviewed journals. (BioRxiv : https://biorxiv.org/cgi/content/short/2024.12.05.626944v1)
- Synaptic Vesicle glycoprotein2A knockout in parvalbumin and somatostatin interneuronsdrives seizuresin the postnatal mouse brain. Bartholome O, Neirinckx V, De La Brassinne O, Desloovere J, Van Den Ackerveken P, Raedt R and Rogister B.2024. DOI: 10.1523/JNEUROSCI.1169-24.2024.
- Epigenetic profiles of elevated cell free circulating H3.1 nucleosomes as potential biomarkers for non-Hodgkin lymphoma. Van den Ackerveken P, Lobbens A, Pamart D, Kotronoulas A, Rommelaere G, Eccleston M, Herzog M. SciRep. 2023 Sep 28;13(1):16335. doi: 10.1038/s41598-023-43520-0. PMID: 37770512; PMCID: PMC10539380.
- Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1. Veithen M, Huyghe A, Van Den Ackerveken P, Fukada SI, Kokubo H, Breuskin I, Nguyen L, Delacroix L, Malgrange B. Cells. 2023 Aug25;12(17):2148. doi: 10.3390/cells12172148. PMID: 37681879; PMCID: PMC10486728.
- Serial profiling of cell-free DNA and nucleosome histone modifications in cell cultures. Ungerer V, Bronkhorst AJ, Van den Ackerveken P, Herzog M, Holdenrieder S.SciRep. 2021 May 4;11(1):9460. doi: 10.1038/s41598-021-88866-5.PMID: 33947882
- A novel proteomics approach to epigenetic profiling of circulating nucleosomes. Van den Ackerveken P, Lobbens A, Turatsinze JV, Solis-MezarinoV, Völker-Albert M, Imhof A, Herzog M.SciRep. 2021 Mar 31;11(1):7256. doi: 10.1038/s41598-021-86630-3.
- Anxiety-like features and spatial memory problems as a consequence ofhippocampal SV2A expression.SerranoME, BartholoméO, Van den Ackerveken P, Ferrara A, Rogister B, Plenevaux A, Tirelli E.PLoS One. 2019 Jun 5;14(6):e0217882. doi: 10.1371/journal.pone.0217882.
- Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration. Willems E, Dedobbeleer M, DigregorioM, Lombard A, Goffart N, LumapatPN, Lambert J, Van den Ackerveken P, Szpakowska M, ChevignéA, Scholtes F, Rogister B.Oncogene. 2019 Jan;38(1):73-87. doi: 10.1038/s41388-018-0437-3.
- The miR-183/ItgA3 axis is a key regulator of prosensoryarea during early inner ear development. Van den Ackerveken P*, Mounier A*, HuygheA, Sacheli R, VanlerberghePB, Volvert ML, Delacroix L, Nguyen L, Malgrange B.CellDeath Differ. 2017 Dec;24(12):2054-2065. doi: 10.1038/cdd.2017.127.
- Puzzling Out Synaptic Vesicle 2 Family Members Functions.; BartholomeO, Van den Ackerveken P, Sánchez Gil J, de la Brassinne BonardeauxO, Leprince P, Franzen R, Rogister B.Front Mol Neurosci. 2017 May 22;10:148. doi: 10.3389/fnmol.2017.00148.
- Development and Validation of a New Mouse Model to Investigate the Role of SV2A in Epilepsy.Menten-Dedoyart C, Serrano Navacerrada ME, BartholomeO, Sánchez Gil J, Neirinckx V, WisletS, Becker G, Plenevaux A, Rogister B*, Van den Ackerveken P*. PLoS One. 2016 Nov 18;11(11):e0166525. doi: 10.1371/journal.pone.0166525. eCollection2016.PMID: 27861538
- MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Van den Ackerveken P*, HuygheA*, Sacheli R, PrévotPP, Thelen N, RenauldJ, Thiry M, Delacroix L, Nguyen L, Malgrange B.Cell Rep. 2015 Oct 6;13(1):31-42. doi: 10.1016/j.celrep.2015.08.054.
- Gene transfer in inner ear cells: a challenging race. SacheliR, Delacroix L, VandenackervekenP, Nguyen L, Malgrange B.Gene Ther. 2013 Mar;20(3):237-47. doi: 10.1038/gt.2012.51.
- Oxidative stress in the cochlea: an update.PoirrierAL, PincemailJ, Van Den Ackerveken P, Lefebvre PP, Malgrange B.CurrMed Chem. 2010;17(30):3591-604. doi: 10.2174/092986710792927895.
- Ototoxic drugs: difference in sensitivity between mice and guinea pigs. PoirrierAL, Van den Ackerveken P, Kim TS, Vandenbosch R, Nguyen L, Lefebvre PP, Malgrange B.ToxicolLett. 2010 Mar 1;193(1):41-9. doi: 10.1016/j.toxlet.2009.12.003.
Timeline
Head of Translational Science Unit
Volition Rx
05.2023 - Current
R&D Project Manager and Team Leader
Volition Rx
09.2017 - 05.2023
Senior R&D Reserach Scientist (Post-doc)
ULiège
08.2015 - 07.2017
R&D Scientist ( PhD Student)
ULiège
10.2010 - 07.2015
Bioasafety
UNamur
Ph.D. - Biomedical And Pharmacentical Sciences
ULiège
FELASA C
ULiège
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