Kavita Mehta
Ph.D Student
Ghent
Overview
2
2
years of professional experience
5
5
years of post-secondary education
Work History
Senior research fellow
Jawaharlal Nehru Centre for Advanced Scintific Research
1 2019 - 03.2022
- Project title: Engineering conditionally replication-competent SARs CoV-2 viral molecular clones and evaluation of cross-variant neutralization: Constructed viral molecular clones of SARs-CoV-2 lacking two crucial structural genes (M and N). The viral clones proliferate only in engineered cell-lines (Vero-E6, BHK-21, Calu-3) expressing these missing genes
- Supervisor: Prof Udaykumar Ranga
Junior research fellow
Jawaharlal Nehru Centre for Advanced Scintific Research
01.2017 - 01.2019
- Project title: Population-based research studies to understand disease dynamics towards effective management, Prevention and treatment of HIV/AIDS, including co-morbidities and co-infections: Developed TILDA to characterize HIV-1 latent reservior. The assay is applicable to the diverse genetic subtypes of HIV-1.
- Supervisor: Prof Udaykumar Ranga
Education
Ph.D. - Health Sciences
Ugent
Ghent, Belgium 04.2001 -
M.Sc. Biotechnology -
DBT Bhimtal, Kumaun University Nainital, Uttarakhand
Nainital, Uttarakhand 08.2015 - 05.2017
Bachelor of Science -
Punjabi University, Patiala, Punjab
Patiala, Punjab 05.2012 - 05.2015
Skills
Sequencing and analysis
Cell Culture
Virus culture
Hands-on experience
Softwares
Courses
2023
- Virus Evolution and Molecular Epidemology (VEME) : Phylogenetic inference module
- HIV Reservoir Characterization Workshop: HCRC Ghent
2022
- Applied Statistic: from Basics to Regression Modelling
Conferences
2023
- Poster- Determination of HIV-1 Subtype, Prediction of Co-receptor Tropism and Drug Resistance Mutations by Partial Sequencing of HIV Env and Pol in the 2000HIV Cohort at 10th HIV Cure Symposium, Ghent
- Poster- Determination of HIV-1 Subtype and Prediction of Co-receptor Tropism by Partial Sequencing of HIV Env in the 2000HIV Cohort at VEME, Stellenbosch
2021
- Poster- Engineering conditionally replication-competent (CRC) SARS-CoV-2 viral molecular clones at AFM and In-house symposium, JNCASR, Bengaluru
Publications
- Mehta, K. et al. An Improved Tat/Rev Induced Limiting Dilution Assay With En-hanced Sensitivity and Breadth of Detection. Front. Immunol. 12,1-14 (2021).
- Bhange, D. et al. The Evolution of Regula-tory Elements in the Emerging Promoter-Variant Strains of HIV-1 Subtype C. Front. Microbiol. 12, 3442 (2021).
- Ali H, Bhange D, Mehta K, et al. An emerg-ing and variant viral promoter of HIV-1 subtype C exhibits low-level gene expres-sion noise. Retrovirology 18, 1-12 (2021).
Timeline
Junior research fellow
Jawaharlal Nehru Centre for Advanced Scintific Research
01.2017 - 01.2019
M.Sc. Biotechnology -
DBT Bhimtal, Kumaun University Nainital, Uttarakhand
08.2015 - 05.2017
Bachelor of Science -
Punjabi University, Patiala, Punjab
05.2012 - 05.2015
Ph.D. - Health Sciences
Ugent
04.2001 -
Senior research fellow
Jawaharlal Nehru Centre for Advanced Scintific Research
1 2019 - 03.2022