Itishri Sahu

Experienced scientist with a strong background in research and analysis. Proficient in experimental design, data analysis, and interpretation across various scientific disciplines. Demonstrated ability to contribute to impactful research projects and collaborate effectively with interdisciplinary teams.

• Self-replicating RNA molecules comprising a sequence encoding non-structural alphavirus proteins and a sequence encoding a SARS-CoV-2 (WO2021255270A1)
• Patent 1 for ionizable lipids for saRNA/mRNA: Lipid nanoparticles for oligonucleotide delivery (WO2023078954A1)
• Patent 2 for ionizable lipids for saRNA/mRNA: Lipid nanoparticles for oligonucleotide delivery (WO2023078950A1)
• Patent 3 for ionizable lipids for saRNA/mRNA: Lipid nanoparticles for oligonucleotide delivery (WO2023078946A1)

• A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity, Molecular Therapy, 2022, Sean McCafferty, A.K.M. Ashiqul Haque, Aster Vandierendonck, Brian Weidensee, Magalie Plovyt, Magdalena Stuchlíková, Nathalie François, Sophie Valembois, Leo Heyndrickx, Johan Michiels, Kevin K. Ariën, Linos Vandekerckhove, Rana Abdelnabi, Caroline S. Foo, Johan Neyts, Itishri Sahu, Niek N. Sanders
• Beta Glycerophosphate- Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes, Sci Rep, 2020, Pelzl L, Sahu I, K Ma, Heizmann D, Al Mamun Bhuyan A, Al Maghout T, Sukkar B, Sharma Y, Marinin I, Rigoni F, Artunc F, Cao H, Ravi Gutti, Voelkl J, Pieske B, Gawaz M, Bakchoul T, Lang F
• Recent developments in mRNA-based protein supplementation therapy to target lung diseases, Mol Ther, 2019, Sahu I, AKM Ashiqul Haque, Brian Weidensee, Petra Weinmann, Kormann MSD
• MicroRNA function in megakaryocytes, Platelets, 2018, Raghuwanshi S, Dahariya S, Musvi SS, Gutti U, Kandi R, Undi RB, Sahu I, Gautam DK, Paddibhatla I, Gutti RK
• Systems biology approach to study the role of miRNA in promoter targeting during megakaryopoiesis, Exp. Cell Res., 2018, Sahu I, Hebalkar R, Kar S, Ts S, Gutti U, Gutti RK
• NFAT5-sensitive Orai1 expression and store-operated Ca2+ entry in megakaryocytes, FASEB J., 2017, Sahu I, Pelzl L, Sukkar B, Fakhri H, Al-Maghout T, Cao H, Hauser S, Gutti R, Gawaz M, Lang F
• Lithium Sensitive ORAI1 Expression, Store Operated Ca2+ Entry and Suicidal Death of Neurons in Chorea-Acanthocytosis, Sci Rep., 2017, Pelzl L, Hauser S, Elsir B, Sukkar B, Sahu I, Singh Y, Höflinger P, Bissinger R, Jemaà M, Stournaras C, Schöls L, Lang F
• Role of Na+/Ca2+ exchangers in therapy resistance of medulloblastoma cells, Cell Physiol Biochem., 2017, Pelzl L, Hosseinzadeh Z, al-Maghout T, Sing Y, Sahu I, Bissinger R, Schmidt S, Alkahtani S, Stournaras C, Toulany M, Lang F
• Sequence and structural difference favor a distinct preference of Wnt3a binding with coreceptor LRP6, J Biomol Struct Dyn., 2015, Sahu I, Mishra S, Undi R, Kandi R, Gutti U, Gutti RK
• MiR-196b-mediated translation regulation of mouse insulin2 via the 5'UTR, PLoS One, 2014, Panda AC, Sahu I, Kulkarni SD, Martindale JL, Abdelmohsen K, Vindu A, Joseph J, Gorospe M, Seshadri V

• VLAIO grant CAR-NK cell therapy (0.4 Mil Euro)- Granted Dec 2023 HBC.2023.0682.
• VLAIO grant RSV (0.3 Mil Euro)- Granted Dec 2022 HBC.2022.0729.
• Award for Research proficiency 2019 by School of Life sciences, UoH.
• Best Poster- 6th International Lung health by ERS
• DAAD Fellowship, Germany (2015-2017).
• Awarded Senior Research Fellowship from Center for Scientific and Industrial research, India.

• Project Management- Vlerick Business School
• FELASA-B

• Operations oversight.
• Innovation management.
• Strategic planning.
• Data interpretation.
• Attention to details.
• Resource Management.
• Problem solving abilities.
• Cross functional team coordination.
• MS Projects.