Atiruj Theppawong
Summary
Organized and dependable candidate successful at managing multiple priorities with a positive attitude. Willingness to take on added responsibilities to meet team goals.
Overview
13
13
years of professional experience
1
1
Certification
Work History
Lab analyst (level 3)
Eurofins PSS Insourcing Solutions
01.2024 - Current
- Serving pharmaceutical company as a contractor
- Participate in quality control (QC) studies and mainly work on R&D studies related to polymer products and some client products
- Participate in method development and method validation using Empower and Fusion QbD
- Participate in an investigation on R&D production (impacting on 1M business revenue)
- Working following European Pharmacopoeia (EP) and USP under GMP and GDP environments
- Willing to extend expertise in diversifying research area
- Trained new team members on laboratory techniques, equipment usage, and safety protocols to maintain a high level of productivity.
- Prioritized work assigned, maintained accurate records of work performed and initiated corrective action in case of defective records or inadequate care plans.
- Trained and supervised junior technicians in laboratory protocols.
Postdoctoral Researcher
UGent
10.2023 - 01.2024
- Involvement in and contribution to other projects: Proteolysis-targeting chimera (PROTACs) and 5HP2Os for protein lipidation projects (for vaccine or bioconjugation tools)
- Overcame technical challenges by troubleshooting equipment issues or refining experimental procedures as necessary.
- Presented research findings at international conferences, fostering knowledge exchange among peers.
- Performed scientific research on multiple projects.
Junior Postdoctoral Researcher
UGent
09.2020 - 09.2022
- Research scope: “Synthesis and Optimization Strategies of Bioengineered Cyclic Peptides for Improving Therapeutic Drug Profiles”
- Main responsibilities: To optimize peptide synthesis via multiple strategies (e.g
- Manual, MW and robot)
- To optimize peptide stapling approaches using cholesterol derivatives
- To evaluate the biological properties of purified therapeutic peptides
- To perform the stability analysis (enzyme degradation and human serum)
- Involvement in and contribution to other projects: IOF project: Scaling up of 5HP2Os synthesis, patent application (EP 19160048.5), (alternative choice for maleimide bioconjugation)
- PROTACs project: synthesizing several analogues (peptide based-small molecule) and supervising a Master student
- Hydrogels project: synthesizing peptide hydrogels and study release profile (also formulation)
- Rink amide soluble support (RASS): alternative scale up for peptide synthesis, mg-g scale in solution
- Different stapled peptide strategy: Stability evaluation (Serum vs Enzymatic systems)
- CLiPs project: contributing to synthesize a few analogues (cyclic peptide synthesis and optimization)
- Cells: working with cells for biological readout e.g., Western Blots, Viability assay
- Picobody: synthesizing picobody (40mers) and evaluating the properties
Research Assistant
Chulabhorn Research Institute
07.2014 - 07.2015
- Focus on medicinal chemistry (small molecules) and oncology research (in vitro cell-based assay)
- Outcome: Facile and Divergent Synthesis of Lamellarins and Lactam-Containing Derivatives with Improved Drug Likeness and Biological Activities, Chemistry - An Asian Journal, 2015, 10(12), pp 2631–2650
- Participated actively in regular meetings with fellow researchers to discuss project updates, challenges faced, and lessons learned during ongoing activities.
- Collaborated with other researchers to develop successful research strategies.
Research Assistant
Chiang Mai University
01.2011 - 01.2012
- Focus on microbiology (biotransformation/fermentation) research
- Main responsibilities: To isolate and purify of artemisinin derivatives from fermentation batch from yeast (Geotrichum sp.)
- To cultivate Gram + (Streptococcus sp.) and Gram – (E.coli, P. Aeruginosa) bacteria for antimicrobial evaluation
Education
Ph.D. - Bioscience Engineering: Chemistry & Bioprocess Technology
Ghent University (UGent)
07.2019
Master of Science - Chemical Biology
Chulabhorn Graduate Institute (CGI)
06.2014
Bachelor of Science - Biochemistry and Biochemical Technology
Chiang Mai University (CMU)
Chiang Mai, Thailand10.2011
Skills
- Desire to learn
- Logical thinking
- Good team player
- Able to work in a multicultural environment
- Method development/validation
- Analytical skills (Problem-solving, Data and metrics interpreting)
- Chemical and biological laboratory safety (GLP, BSL1 and 2) and also in GMP environment
- Writing project proposals/reports for scientific research
- Quality Control (QC)
- Proofreading scientific manuscripts/scientific reviewer
- Good interpersonal, verbal, and written communication skills with the ability to balance multiple priorities
- Scientific outputs
- Sample Preparation
- Laboratory techniques
- Complex Problem-Solving
Certification
- BEERx: The Science of Beer course (issued by Wageningen University & Research)
- Medicinal Chemistry: The Molecular Basis of Drug Discovery course (issued by Davidson College)
- Medicinal Chemistry course 2018 (organized by KU Leuven and Janssen Pharmaceutica)
Languages
Thai
Bilingual or Proficient (C2)
English
Bilingual or Proficient (C2)
Dutch
Intermediate (B1)
French
Elementary (A2)
Peer reviewer in scientific journal
- Chemistry & biodiversity
- ChemistrySelect Journals
Motivation
With 7+ years of experience in chemistry and biology, I specialize in crafting both small and large molecules. My aim is to pioneer treatments for a range of diseases, driven by an insatiable scientific curiosity and problem-solving zeal. Committed to advancing the field, I thrive as a collaborative team player with a knack for creative thinking, pushing boundaries in diverse research areas.
Personal Information
- Nationality: Belgian, No work permit required in EU zone
- Driving License: Belgian license B
Awards
- FWO postdoctoral award: obtained outstanding results (score: 6/7, excellent)
- Scholarship Award from Erasmus Mundus (LOTUS+ project): only 5% selection from > 3500 applications
- The best Atom Award (nominated from biochemistry and biotechnology, Faculty of Science, Chiang Mai University)
- Certificate of Academic Excellence (Faculty of Science, Chiang Mai University)
Publications
- Proximity-Induced Ligation and One-Pot Macrocyclization of 1,4-Diketone-Tagged Peptides Derived from 2,5-Disubstituted Furans upon Release from the Solid Support, Org. Lett., 2023, 25, 36, 6618–6622
- Synthesis of 1,4-Thiazepane-Based Curcuminoids with Promising Anticancer Activity, Chemistry - A European Journal, 2019, 25, 54, 12583–12600
- Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress, European Journal of Medicinal Chemistry, 2016, 123, 727–736
Training
Flow cytometry (Introduction/theory/design exp)
Recruitment experience in selecting potential candidate
Additional Information
Chemistry:
- Organic/peptide synthesis
- NMR, FTIR, HPLC, LC-MS, UPLC-QDa, GC-MS, UV/VIS, MALDI-TOF
- Software: Empower, chemstation, Bruker, Openlab
Biology:
- Aseptic technique for BSL
- Cultivate microorganisms, mammalian cells
- Cytotoxicity/ Western blot
- Microscope
- Transwell experiments
Timeline
Lab analyst (level 3)
Eurofins PSS Insourcing Solutions
01.2024 - Current
Postdoctoral Researcher
UGent
10.2023 - 01.2024
Junior Postdoctoral Researcher
UGent
09.2020 - 09.2022
Research Assistant
Chulabhorn Research Institute
07.2014 - 07.2015
Research Assistant
Chiang Mai University
01.2011 - 01.2012
Ph.D. - Bioscience Engineering: Chemistry & Bioprocess Technology
Ghent University (UGent)
Master of Science - Chemical Biology
Chulabhorn Graduate Institute (CGI)
Bachelor of Science - Biochemistry and Biochemical Technology
Chiang Mai University (CMU)
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